Cellosaurus logo
expasy logo

Cellosaurus DU145 fat-1 (CVCL_E6ZG)

[Text version]
Cell line name DU145 fat-1
Accession CVCL_E6ZG
Resource Identification Initiative To cite this cell line use: DU145 fat-1 (RRID:CVCL_E6ZG)
Comments From: Lim, Kyu; Department of Biochemistry, Chungnam National University Medical School; Daejeon, South Korea.
Population: Caucasian.
Characteristics: Applicable for studies investigating the effects of endogenous omega3-polyunsaturated fatty acids (ABM=T6271).
Doubling time: 20-30 hours (ABM=T6271).
Genetic integration: Method=Transfection; Gene=UniProtKB; Q9NEQ0; Caenorhabditis elegans omega-3 fatty acid desaturase fat-1.
Genetic integration: Method=Transfection; Gene=UniProtKB; P00552; Transposon Tn5 neo.
Derived from site: Metastatic; Brain; UBERON=UBERON_0000955.
Sequence variations
  • Mutation; HGNC; HGNC:1787; CDKN2A; Simple; p.Asp84Tyr (c.250G>T) (p.Arg98Leu, c.293G>T); ClinVar=VCV000376306; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; HGNC:9884; RB1; Simple; p.Lys715Ter (c.2143A>T); ClinVar=VCV001786615; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; HGNC:11389; STK11; Simple; p.Lys178fs*86 (c.532_536delAAGCC); Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Pro223Leu (c.668C>T); ClinVar=VCV000234214; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Val274Phe (c.820G>T); ClinVar=VCV000376674; Zygosity=Heterozygous (from parent cell line).
Disease Prostate carcinoma (NCIt: C4863)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0105 (DU145)
Sex of cell Male
Age at sampling 69Y
Category Cancer cell line
Cross-references
Cell line collections (Providers) ABM; T6271
Entry history
Entry creation10-Apr-2025
Last entry update10-Apr-2025
Version number1