Cellosaurus logo
expasy logo

Cellosaurus ROM1 (CVCL_E6Z5)

[Text version]
Cell line name ROM1
Accession CVCL_E6Z5
Resource Identification Initiative To cite this cell line use: ROM1 (RRID:CVCL_E6Z5)
Comments Population: Caucasian.
Doubling time: 48-72 hours (ABM=T0413).
Genetic integration: Method=Transduction; Gene=UniProtKB; P03070; SV40 large T antigen.
Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40) (Note=tsA58).
Donor information: Established from a patient with recurrent otitis media normal hearing (PubMed=37899851).
Caution: The same name is used for the primary culture described in PubMed=32433794 and the immortalized cell line described in PubMed=37899851.
Derived from site: In situ; Ear, middle ear; UBERON=UBERON_0001756.
Cell type: Epithelial cell; CL=CL_0000066.
Disease Otitis media (NCIt: C34885)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling 1Y4M
Category Transformed cell line
Publications

PubMed=32433794; DOI=10.1002/lary.28687
Espahbodi M., Samuels T.L., McCormick C., Khampang P., Yan K., Marshall S., McCormick M.E., Chun R.H., Harvey S.A., Friedland D.R., Johnston N., Kerschner J.E.
Analysis of inflammatory signaling in human middle ear cell culture models of pediatric otitis media.
Laryngoscope 131:410-416(2021)

PubMed=37899851; DOI=10.1002/lio2.1141; PMCID=PMC10601576
Blaine-Sauer S., Samuels T.L., Khampang P., Yan K., McCormick M.E., Chun R.H., Harvey S.A., Friedland D.R., Johnston N., Kerschner J.E.
Establishment of novel immortalized middle ear cell lines as models for otitis media.
Laryngoscope Investig. Otolaryngol. 8:1428-1435(2023)

Cross-references
Cell line collections (Providers) ABM; T0413
Entry history
Entry creation10-Apr-2025
Last entry update10-Apr-2025
Version number1