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Cellosaurus GG8 (CVCL_E6X6)

[Text version]
Cell line name GG8
Accession CVCL_E6X6
Resource Identification Initiative To cite this cell line use: GG8 (RRID:CVCL_E6X6)
Comments Characteristics: Teatment with INFG renders the cell line immunogenic and results in T cell proliferation (PubMed=9384677).
Genetic integration: Method=Transfection; Gene=HGNC; HGNC:1700; CD80.
Derived from site: Metastatic; Ascites; UBERON=UBERON_0007795.
Disease Ovarian serous cystadenocarcinoma (NCIt: C7978)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_A1IB (GG)
Sex of cell Female
Age at sampling Age unspecified
Category Cancer cell line
Publications

PubMed=9384677
Guckel B., Lindauer M., Rudy W., Habicht A., Siebels M., Kaul S., Bastert G., Meuer S.C., Moebius U.
CD80-transfected human breast and ovarian tumor cell lines: improved immunogenicity and induction of cytolytic CD8+ T lymphocytes.
Cytokines Mol. Ther. 1:211-221(1995)

PubMed=10359208; DOI=10.1038/sj.cgt.7700050
Guckel B., Meyer G.C., Rudy W., Batrla R., Meuer S.C., Bastert G., Wallwiener D., Moebius U.
Interleukin-12 requires initial CD80-mediated T-cell activation to support immune responses toward human breast and ovarian carcinoma.
Cancer Gene Ther. 6:228-237(1999)

Entry history
Entry creation10-Apr-2025
Last entry update10-Apr-2025
Version number1