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Cellosaurus JFE-21 (CVCL_E6ME)

[Text version]
Cell line name JFE-21
Accession CVCL_E6ME
Resource Identification Initiative To cite this cell line use: JFE-21 (RRID:CVCL_E6ME)
Comments Population: Japanese.
Doubling time: 55.8 +- 7.0 h hours (PubMed=39878900).
Karyotypic information: Near tetraploid karytotype (PubMed=39878900).
Genetic integration: Method=Transduction; Gene=HGNC; HGNC:1582; CCND1.
Genetic integration: Method=Transduction; Gene=HGNC; HGNC:1773; CDK4 (Note=With p.Arg24Cys).
Genetic integration: Method=Transduction; Gene=HGNC; HGNC:11730; TERT.
Genetic integration: Method=Transduction; Gene=UniProtKB; P33967; B.cereus Bsr.
Genetic integration: Method=Transduction; Gene=UniProtKB; P00557; Escherichia coli hygromycin-B 4-O-kinase (hph) (HygR).
Derived from site: In situ; Ovary; UBERON=UBERON_0000992.
Disease Ovarian endometrioid adenocarcinoma (NCIt: C7979)
Endometrioid carcinoma of ovary (ORDO: Orphanet_454723)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling 46Y
Category Telomerase immortalized cell line
STR profile Source(s): PubMed=39878900

Markers:
AmelogeninX
CSF1PO11,12
D3S135814,17
D5S8189,11
D7S82011,12
D8S117910,15
D13S31710
D16S53910,11
D18S5115,16
D21S1129,30
FGA21,23
Penta D9
Penta E5,15
TH016,9
TPOX8,11
vWA17,18

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Publications

PubMed=39878900; DOI=10.1007/s13577-025-01176-0; PMCID=PMC11779770
Hoshino H., Akama T.O., Inoue D., Moritani S., Shigeto S., Matsuda K., Yoshida H., Yonemoto N., Fukushima M., Yoshida Y., Kobayashi M.
Establishment of a human ovarian endometrioid carcinoma cell line by constitutive expression of cyclin-dependent kinase 4, cyclin D1 and telomerase reverse transcriptase.
Hum. Cell 38:47.1-47.12(2025)

Entry history
Entry creation10-Apr-2025
Last entry update10-Apr-2025
Version number1