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Cellosaurus TD-15 corrected clone H02 (CVCL_E6KW)

[Text version]
Cell line name TD-15 corrected clone H02
Synonyms TD-15 (isogenic correction)
Accession CVCL_E6KW
Resource Identification Initiative To cite this cell line use: TD-15 corrected clone H02 (RRID:CVCL_E6KW)
Comments From: Clinical Biospecimen Imaging and Genetic (C-BIG) Repository, Montreal Neurological Institute, McGill University; Montreal; Canada.
Population: Caucasian.
Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
Sequence variations
  • Mutation; HGNC; HGNC:11179; SOD1; Simple_corrected; p.Ile114Thr (c.341T>C) (I113T); ClinVar=VCV000197145; Zygosity=Heterozygous; Note=By CRISPR/Cas9 (PubMed=34500068).
Disease Amyotrophic lateral sclerosis 1 (NCIt: C168749)
Amyotrophic lateral sclerosis (ORDO: Orphanet_803)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_E6KV (TD-15)
Sex of cell Female
Age at sampling 45Y
Category Induced pluripotent stem cell
STR profile Source(s): PubMed=34500068

Markers:
AmelogeninX
CSF1PO12,13
D5S81812,13
D7S8209,11
D13S31711
D16S5399,12
D21S1128,31.2
TH017,8
TPOX11
vWA16,17

Run an STR similarity search on this cell line
Web pages Provider; C-BIG; -; https://cbigr-open.loris.ca/C-BIG_ipsc_catalog_august_2023.pdf
Publications

PubMed=34500068; DOI=10.1016/j.ymeth.2021.09.002
Deneault E., Chaineau M., Nicouleau M., Castellanos-Montiel M.J., Franco-Flores A.K., Haghi G., Chen C.X.-Q., Abdian N., Shlaifer I., Beitel L.K., Durcan T.M.
A streamlined CRISPR workflow to introduce mutations and generate isogenic iPSCs for modeling amyotrophic lateral sclerosis.
Methods 203:297-310(2022)

Entry history
Entry creation10-Apr-2025
Last entry update10-Apr-2025
Version number1