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Cellosaurus Hela M VPS13C-KO clone 2 (CVCL_E6IR)

[Text version]
Cell line name Hela M VPS13C-KO clone 2
Synonyms VPS13C(KO) HeLa clone 2
Accession CVCL_E6IR
Resource Identification Initiative To cite this cell line use: Hela M VPS13C-KO clone 2 (RRID:CVCL_E6IR)
Comments Population: African American.
Knockout cell: Method=CRISPR/Cas9; HGNC; HGNC:23594; VPS13C.
Transformant: NCBI_TaxID; 333761; Human papillomavirus type 18 (HPV18).
Derived from site: In situ; Uterus, cervix; UBERON=UBERON_0000002.
Disease Human papillomavirus-related endocervical adenocarcinoma (NCIt: C27677)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_R965 (HeLa M)
Sex of cell Female
Age at sampling 30Y6M
Category Cancer cell line
Publications

PubMed=35657605; DOI=10.1083/jcb.202106046; PMCID=PMC9170524
Hancock-Cerutti W.F., Wu Z., Xu P., Yadavalli N.V., Leonzino M., Tharkeshwar A.K., Ferguson S.M., Shadel G.S., De Camilli P.
ER-lysosome lipid transfer protein VPS13C/PARK23 prevents aberrant mtDNA-dependent STING signaling.
J. Cell Biol. 221:e202106046.1-e202106046.19(2022)

Entry history
Entry creation10-Apr-2025
Last entry update10-Apr-2025
Version number1