Cellosaurus cell line CI-huEGC (CVCL

Cellosaurus CI-huEGC (CVCL_E6BG)

[Text version]

Cell line name

CI-huEGC

Synonyms

CIK

Accession

CVCL_E6BG

Resource Identification Initiative

To cite this cell line use: CI-huEGC (RRID:CVCL_E6BG)

Comments

Characteristics: Transduced with a lentiviral library consisting of 33 genes, some of which are retained in the immortalized cell line (CI-SCREEN) (PubMed=37153631).
Genetic integration: Method=Transduction; Gene=HGNC; HGNC:5360; ID1.
Genetic integration: Method=Transduction; Gene=HGNC; HGNC:7553; MYC.
Genetic integration: Method=Transduction; Gene=MGI; MGI:88174; Bmi1.
Genetic integration: Method=Transduction; Gene=MGI; MGI:1919200; Nanog.
Genetic integration: Method=Transduction; Gene=MGI; MGI:99187; Zfp42.
Genetic integration: Method=Transduction; Gene=UniProtKB; P03126; Human papillomavirus type 16 protein E6.
Genetic integration: Method=Transduction; Gene=UniProtKB; P03129; Human papillomavirus type 16 protein E7.
Genetic integration: Method=Transduction; Gene=Hepatitis C virus core protein.
Transformant: NCBI_TaxID; 333760; Human papillomavirus type 16 (HPV16).
Derived from site: In situ; Colon, myenteric nerve plexus; UBERON=UBERON_8410058.
Cell type: Enteric glial cell; CL=CL_4040002.

HLA typing

Source: PubMed=37153631

Class I
HLA-A	A*01:01,30:01
HLA-B	B*07:02,08:01
HLA-C	C*07:01,12:03
Class II
HLA-DQ	DQA1*01:02,01:03
	DQB1*06:02,06:03
HLA-DR	DRB1*13:01,15:01

Species of origin

Homo sapiens (Human) (NCBI Taxonomy: 9606)

Sex of cell

Female

Age at sampling

75Y

Category

Transformed cell line

STR profile

Source(s): InSCREENeX=INS-CI-1030

Markers:

Amelogenin	X
CSF1PO	11,12
D2S1338	17,19
D3S1358	17,18
D5S818	11,13
D7S820	11,13
D8S1179	13,14
D13S317	11,14
D16S539	12,13
D18S51	13,14
D19S433	15
D21S11	30,32.2
FGA	21
TH01	6,8
TPOX	8
vWA	17

Web pages

Provider; InSCREENeX; INS-CI-1030; https://www.inscreenex.de/product/ci-huegc/

Publications

PubMed=37153631; DOI=10.3389/fncel.2023.1170309; PMCID=PMC10158601
Zanoletti L., Valdata A., Nehlsen K., Faris P., Casali C., Cacciatore R., Sbarsi I., Carriero F., Arfini D., van Baarle L., De Simone V., Barbieri G., Raimondi E., May T., Moccia F., Bozzola M., Matteoli G., Comincini S., Manai F.
Cytological, molecular, cytogenetic, and physiological characterization of a novel immortalized human enteric glial cell line.
Front. Cell. Neurosci. 17:1170309.1-1170309.16(2023)

Entry history

Entry creation

10-Apr-2025

Last entry update

10-Apr-2025

Version number