ID   NIH 3T3 hRRAS2 G23A
AC   CVCL_E5LH
RX   PubMed=36476833;
CC   Characteristics: Displays transforming activity in focus formation assays (PubMed=36476833).
CC   Genetic integration: Method=Transfection; Gene=HGNC; HGNC:17271; RRAS2 (Note=With p.Gly23Ala and a N-terminal HA tag).
CC   Genetic integration: Method=Transfection; Gene=UniProtKB; P00552; Transposon Tn5 neo.
CC   Derived from site: In situ; Whole embryo; UBERON=UBERON_0000922.
CC   Cell type: Fibroblast; CL=CL_0000057.
CC   Breed/subspecies: NIH Swiss.
OX   NCBI_TaxID=10090; ! Mus musculus (Mouse)
HI   CVCL_0594 ! NIH 3T3
SX   Male
AG   Embryo
CA   Spontaneously immortalized cell line
DT   Created: 10-04-25; Last updated: 10-04-25; Version: 1
//
RX   PubMed=36476833; DOI=10.1038/s41388-022-02563-9; PMCID=PMC9883167;
RA   Clavain L., Fernandez-Pisonero M.I., Movilla N., Lorenzo-Martin L.F.,
RA   Nieto B., Abad A., Garcia-Navas R., Llorente-Gonzalez C.,
RA   Sanchez-Martin M., Vicente-Manzanares M., Santos E., Alarcon B.,
RA   Garcia-Aznar J.M., Dosil M., Bustelo X.R.;
RT   "Characterization of mutant versions of the R-RAS2/TC21 GTPase found
RT   in tumors.";
RL   Oncogene 42:389-405(2023).
//