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Cellosaurus DEM (CVCL_E559)

[Text version]
Cell line name DEM
Accession CVCL_E559
Resource Identification Initiative To cite this cell line use: DEM (RRID:CVCL_E559)
Comments Part of: 10th International Histocompatibility Workshop (10IHW) cell line panel.
Population: Caucasian; German.
Transformant: NCBI_TaxID; 10376; Epstein-Barr virus (EBV).
Omics: MHC region genome.
Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
Cell type: B-cell; CL=CL_0000236.
HLA typing Source: IPD-IMGT/HLA=11627
Class I
HLA-AA*02:01:01:01
HLA-BB*57:01:01
HLA-CC*06:02:01:01
Class II
HLA-DPDPA1*01
DPB1*03:01:01,04:01:01
HLA-DQDQA1*01:02:02,03:01
DQB1*05:02:01,03:02:01
HLA-DRDRA*01:01
DRB1*04:01:01,16:02:01
DRB4*01:01
DRB5*02
DRB6*02:02
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling Age unspecified
Category Transformed cell line
Publications

DOI=10.1007/978-1-4612-3552-1_2
Yang S.Y., Milford E.L., Hammerling U., Dupont B.
Description of the reference panel of B-lymphoblastoid cell lines for factors of the HLA system: the B-cell line panel designed for the Tenth International Histocompatibility Workshop.
(In book chapter) Immunobiology of HLA. Volume I. Histocompatibility testing 1987; Dupont B. (eds.); pp.11-19; Springer; New York; USA (1989)

DOI=10.1007/978-1-4612-3552-1_4
Mickelson E.M., Reinsmoen N.L., Robbins F.-M., Hartzman R.J., Odum N., Svejgaard A., Farrell C., Honeyman M.C., Flomenberg N., Sell T.W., Eckels D.D.
HLA-Dw and HLA-DP typing of the reference panel of B-lymphoblastoid cell lines.
(In book chapter) Immunobiology of HLA. Volume I. Histocompatibility testing 1987; Dupont B. (eds.); pp.38-42; Springer; New York; USA (1989)

DOI=10.1007/978-1-4612-3552-1_5
Yang S.Y.
Assignment of HLA-A and HLA-B antigens for the reference panel of B-lymphoblastoid cell lines determined by one-dimensional isoelectric focusing (lD-IEF) gel electrophoresis.
(In book chapter) Immunobiology of HLA. Volume I. Histocompatibility testing 1987; Dupont B. (eds.); pp.43-44; Springer; New York; USA (1989)

DOI=10.1007/978-1-4612-3552-1_6
Knowles R.W.
Assignment of HLA-class II alpha and beta chain 2-D gel patterns for the workshop reference panel of B-lymphoblastoid cell lines.
(In book chapter) Immunobiology of HLA. Volume I. Histocompatibility testing 1987; Dupont B. (eds.); pp.44-46; Springer; New York; USA (1989)

DOI=10.1007/978-1-4612-3552-1_7
Flomenberg N.
Assignment of T-cell-defined (TCD) HLA class II specificities for the reference panel of B-lymphoblastoid cell lines.
(In book chapter) Immunobiology of HLA. Volume I. Histocompatibility testing 1987; Dupont B. (eds.); pp.46-48; Springer; New York; USA (1989)

PubMed=8813743; DOI=10.1111/j.1399-0039.1996.tb02596.x
Prasad V.K., Yang S.Y.
Allele assignment for HLA-A, -B, and -C genes to the Tenth International Histocompatibility Workshop cell lines.
Tissue Antigens 47:538-546(1996)

PubMed=28360230; DOI=10.1101/gr.213538.116; PMCID=PMC5411776
Norman P.J., Norberg S.J., Guethlein L.A., Nemat-Gorgani N., Royce T., Wroblewski E.E., Dunn T., Mann T., Alicata C., Hollenbach J.A., Chang W.-H., Shults Won M., Gunderson K.L., Abi-Rached L., Ronaghi M., Parham P.
Sequences of 95 human MHC haplotypes reveal extreme coding variation in genes other than highly polymorphic HLA class I and II.
Genome Res. 27:813-823(2017)

PubMed=29171935; DOI=10.1111/tan.13184
Turner T.R., Hayhurst J.D., Hayward D.R., Bultitude W.P., Barker D.J., Robinson J., Madrigal J.A., Mayor N.P., Marsh S.G.E.
Single molecule real-time DNA sequencing of HLA genes at ultra-high resolution from 126 international HLA and immunogenetics workshop cell lines.
HLA 91:88-101(2018)

PubMed=30844424; DOI=10.1016/j.humimm.2019.03.001; PMCID=PMC6599558
Creary L.E., Guerra S.G., Chong W., Brown C.J., Turner T.R., Robinson J., Bultitude W.P., Mayor N.P., Marsh S.G.E., Saito K., Lam K., Duke J.L., Mosbruger T.L., Ferriola D., Monos D.S., Willis A., Askar M., Fischer G.F., Saw C.L., Ragoussis J., Petrek M., Serra-Pages C., Juan Otero M., Stavropoulos-Giokas C., Dinou A., Ameen R., Al Shemmari S., Spierings E., Gendzekhadze K., Morris G.P., Zhang Q.-H., Kashi Z., Hsu S., Gangavarapu S., Mallempati K.C., Yamamoto F., Osoegawa K., Vayntrub T., Chang C.-J., Hansen J.A., Fernandez-Vina M.A.
Next-generation HLA typing of 382 International Histocompatibility Working Group reference B-lymphoblastoid cell lines: report from the 17th International HLA and Immunogenetics Workshop.
Hum. Immunol. 80:449-460(2019)

Cross-references
Cell line collections (Providers) ECACC; 88052007
Cell line databases/resources dbMHC; 48753
IHW; IHW09007
IPD-IMGT/HLA; 11627
Encyclopedic resources Wikidata; Q54830972
Entry history
Entry creation22-Oct-2012
Last entry update05-Oct-2023
Version number17