ID   ZR-75-1 GRB7 clone 4
AC   CVCL_E4WY
SY   ZR-GRB7 (4)
DR   CancerTools; 154642
RX   PubMed=18351453;
CC   Population: Caucasian.
CC   Sequence variation: Mutation; HGNC; HGNC:5173; HRAS; Simple; p.Glu162Lys (c.484G>A); ClinVar=VCV001034833; Zygosity=Homozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; HGNC:9588; PTEN; Simple; p.Leu108Arg (c.323T>G); Zygosity=Homozygous (from parent cell line).
CC   Genetic integration: Method=Transfection; Gene=HGNC; HGNC:4567; GRB7.
CC   Genetic integration: Method=Transfection; Gene=UniProtKB; P00552; Klebsiella pneumoniae transposon Tn5 neo.
CC   Derived from site: Metastatic; Ascites; UBERON=UBERON_0007795.
DI   NCIt; C4194; Invasive breast carcinoma of no special type
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_0588 ! ZR-75-1
SX   Female
AG   63Y
CA   Cancer cell line
DT   Created: 19-12-24; Last updated: 14-08-25; Version: 3
//
RX   PubMed=18351453; DOI=10.1007/s10549-008-9969-5;
RA   van Agthoven, Ton
RA   Veldscholte, Jos Willibrordus
RA   Smid, Marcel
RA   van Agthoven, Thecla L.A.
RA   Vreede, Lilian
RA   Broertjes, Marieke
RA   de Vries, Ingrid
RA   de Jong, Danielle
RA   Sarwari, Roya
RA   Dorssers, Lambert C.J.
RT   "Functional identification of genes causing estrogen independence of
RT   human breast cancer cells.";
RL   Breast Cancer Res. Treat. 114:23-30(2009).
//