ID   ZR-75-1 GRB7 clone 4
AC   CVCL_E4WY
SY   ZR-GRB7 (4)
DR   CancerTools; 154642
RX   PubMed=18351453;
CC   Population: Caucasian.
CC   Sequence variation: Mutation; HGNC; 5173; HRAS; Simple; p.Glu162Lys (c.484G>A); ClinVar=VCV001034833; Zygosity=Homozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 9588; PTEN; Simple; p.Leu108Arg (c.323T>G); Zygosity=Homozygous (from parent cell line).
CC   Genetic integration: Method=Transfection; Gene=HGNC; HGNC:4567; GRB7.
CC   Genetic integration: Method=Transfection; Gene=UniProtKB; P00552; Transposon Tn5 neo.
CC   Derived from site: Metastatic; Ascites; UBERON=UBERON_0007795.
DI   NCIt; C4194; Invasive breast carcinoma of no special type
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_0588 ! ZR-75-1
SX   Female
AG   63Y
CA   Cancer cell line
DT   Created: 19-12-24; Last updated: 19-12-24; Version: 1
//
RX   PubMed=18351453; DOI=10.1007/s10549-008-9969-5;
RA   van Agthoven T., Veldscholte J.W., Smid M., van Agthoven T.L.A.,
RA   Vreede L., Broertjes M., de Vries I., de Jong D., Sarwari R.,
RA   Dorssers L.C.J.;
RT   "Functional identification of genes causing estrogen independence of
RT   human breast cancer cells.";
RL   Breast Cancer Res. Treat. 114:23-30(2009).
//