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Cellosaurus ZR-75-1 GRB7 clone 3 (CVCL_E4WX)

[Text version]
Cell line name ZR-75-1 GRB7 clone 3
Synonyms ZR-GRB7 (3)
Accession CVCL_E4WX
Resource Identification Initiative To cite this cell line use: ZR-75-1 GRB7 clone 3 (RRID:CVCL_E4WX)
Comments Population: Caucasian.
Genetic integration: Method=Transfection; Gene=HGNC; HGNC:4567; GRB7.
Genetic integration: Method=Transfection; Gene=UniProtKB; P00552; Transposon Tn5 neo.
Derived from site: Metastatic; Ascites; UBERON=UBERON_0007795.
Sequence variations
  • Mutation; HGNC; 5173; HRAS; Simple; p.Glu162Lys (c.484G>A); ClinVar=VCV001034833; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; 9588; PTEN; Simple; p.Leu108Arg (c.323T>G); Zygosity=Homozygous (from parent cell line).
Disease Invasive breast carcinoma of no special type (NCIt: C4194)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0588 (ZR-75-1)
Sex of cell Female
Age at sampling 63Y
Category Cancer cell line
Publications

PubMed=18351453; DOI=10.1007/s10549-008-9969-5
van Agthoven T., Veldscholte J.W., Smid M., van Agthoven T.L.A., Vreede L., Broertjes M., de Vries I., de Jong D., Sarwari R., Dorssers L.C.J.
Functional identification of genes causing estrogen independence of human breast cancer cells.
Breast Cancer Res. Treat. 114:23-30(2009)

Cross-references
Cell line collections (Providers) CancerTools; 154627
Entry history
Entry creation19-Dec-2024
Last entry update19-Dec-2024
Version number1