ID   ZR-75-1 BCAR1 clone 4A12
AC   CVCL_E4WT
SY   ZR-75-1 BCAR1 [4A12]
DR   CancerTools; 154621
RX   PubMed=10639512;
CC   Population: Caucasian.
CC   Sequence variation: Mutation; HGNC; 5173; HRAS; Simple; p.Glu162Lys (c.484G>A); ClinVar=VCV001034833; Zygosity=Homozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 9588; PTEN; Simple; p.Leu108Arg (c.323T>G); Zygosity=Homozygous (from parent cell line).
CC   Genetic integration: Method=Transfection; Gene=HGNC; HGNC:971; BCAR1.
CC   Genetic integration: Method=Transfection; Gene=UniProtKB; P00552; Transposon Tn5 neo.
CC   Derived from site: Metastatic; Ascites; UBERON=UBERON_0007795.
DI   NCIt; C4194; Invasive breast carcinoma of no special type
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_0588 ! ZR-75-1
SX   Female
AG   63Y
CA   Cancer cell line
DT   Created: 19-12-24; Last updated: 19-12-24; Version: 1
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RX   PubMed=10639512; DOI=10.1093/jnci/92.2.112;
RA   Brinkman A., van der Flier S., Kok E.M., Dorssers L.C.J.;
RT   "BCAR1, a human homologue of the adapter protein p130Cas, and
RT   antiestrogen resistance in breast cancer cells.";
RL   J. Natl. Cancer Inst. 92:112-120(2000).
//