Cellosaurus logo
expasy logo

Cellosaurus ZR-75-1 AKT2 pool B (CVCL_E4WS)

[Text version]
Cell line name ZR-75-1 AKT2 pool B
Synonyms ZR-AKT2 pool B
Accession CVCL_E4WS
Resource Identification Initiative To cite this cell line use: ZR-75-1 AKT2 pool B (RRID:CVCL_E4WS)
Comments Population: Caucasian.
Genetic integration: Method=Transfection; Gene=HGNC; HGNC:392; AKT2.
Genetic integration: Method=Transfection; Gene=UniProtKB; P00552; Transposon Tn5 neo.
Derived from site: Metastatic; Ascites; UBERON=UBERON_0007795.
Sequence variations
  • Mutation; HGNC; 5173; HRAS; Simple; p.Glu162Lys (c.484G>A); ClinVar=VCV001034833; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; 9588; PTEN; Simple; p.Leu108Arg (c.323T>G); Zygosity=Homozygous (from parent cell line).
Disease Invasive breast carcinoma of no special type (NCIt: C4194)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0588 (ZR-75-1)
Sex of cell Female
Age at sampling 63Y
Category Cancer cell line
Publications

PubMed=18351453; DOI=10.1007/s10549-008-9969-5
van Agthoven T., Veldscholte J.W., Smid M., van Agthoven T.L.A., Vreede L., Broertjes M., de Vries I., de Jong D., Sarwari R., Dorssers L.C.J.
Functional identification of genes causing estrogen independence of human breast cancer cells.
Breast Cancer Res. Treat. 114:23-30(2009)

Cross-references
Cell line collections (Providers) CancerTools; 154624
Entry history
Entry creation19-Dec-2024
Last entry update19-Dec-2024
Version number1