Cellosaurus ZR-75-1 XI-36 (CVCL_E4M0)
Cell line name | ZR-75-1 XI-36 |
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Synonyms | ZR-75-1 [XI-36] |
Accession | CVCL_E4M0 |
Resource Identification Initiative | To cite this cell line use: ZR-75-1 XI-36 (RRID:CVCL_E4M0) |
Comments | Population: Caucasian. Characteristics: Infected with an amphotropic defective murine retrovirus. Retroviral insertion was used in order to identify genes responsible for estrogen-independence and thus tamoxifen resistant (PubMed=8413311; PubMed=18351453). Characteristics: Gene likely to be responsible to resistance in this cell line is BCAR3 (PubMed=18351453). Selected for resistance to: ChEBI; CHEBI_41774; Tamoxifen. Genetic integration: Method=Transduction; Gene=UniProtKB; P00552; Transposon Tn5 neo. Derived from site: Metastatic; Ascites; UBERON=UBERON_0007795. |
Sequence variations |
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Disease | Invasive breast carcinoma of no special type (NCIt: C4194) |
Species of origin | Homo sapiens (Human) (NCBI Taxonomy: 9606) |
Hierarchy | Parent: CVCL_0588 (ZR-75-1) |
Sex of cell | Female |
Age at sampling | 63Y |
Category | Cancer cell line |
Publications | PubMed=8413311; DOI=10.1210/mend.7.7.8413311 PubMed=18351453; DOI=10.1007/s10549-008-9969-5 |
Cross-references | |
Cell line collections (Providers) | CancerTools; 154583 |
Entry history | |
Entry creation | 19-Dec-2024 |
Last entry update | 19-Dec-2024 |
Version number | 1 |