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Cellosaurus GB2 (CVCL_E4KM)

[Text version]
Cell line name GB2
Accession CVCL_E4KM
Resource Identification Initiative To cite this cell line use: GB2 (RRID:CVCL_E4KM)
Comments Part of: Biliary tract cancer cell line atlas.
Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Population: Caucasian.
Derived from site: In situ; Gallbladder; UBERON=UBERON_0002110.
Disease Gallbladder carcinoma (NCIt: C3844)
Carcinoma of gallbladder and extrahepatic biliary tract (ORDO: Orphanet_56044)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Category Cancer cell line
STR profile Source(s): DepMap=ACH-001961

Markers:
AmelogeninX
CSF1PO11
D3S135814,17
D5S81812,13
D7S8208,10
D8S117916
D13S3178,12
D16S5399,13
D18S5112
D21S1129
FGA22,23
Penta D8,10
Penta E7,10
TH019,9.3
TPOX8
vWA16

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Publications

PubMed=31109923; DOI=10.1158/2159-8290.CD-19-0182; PMCID=PMC6677584
Goyal L., Shi L., Liu L.Y., Fece de la Cruz F., Lennerz J.K., Raghavan S., Leschiner I., Elagina L., Siravegna G., Ng R.W.S., Vu P., Patra K.C., Saha S.K., Uppot R.N., Arellano R.S., Reyes S., Sagara T., Otsuki S., Nadres B., Shahzade H.A., Dey-Guha I., Fetter I.J., Baiev I., Van Seventer E.E., Murphy J.E., Ferrone C.R., Tanabe K.K., Deshpande V., Harding J.J., Yaeger R.D., Kelley R.K., Bardelli A., Iafrate A.J., Hahn W.C., Benes C.H., Ting D.T., Hirai H., Getz G., Juric D., Zhu A.X.-X., Corcoran R.B., Bardeesy N.M.
TAS-120 overcomes resistance to ATP-competitive FGFR inhibitors in patients with FGFR2 fusion-positive intrahepatic cholangiocarcinoma.
Cancer Discov. 9:1064-1079(2019)

PubMed=39026794; DOI=10.1101/2024.07.04.601970; PMCID=PMC11257448
Vijay V., Karisani N., Shi L., Hung Y.-H., Vu P., Kattel P., Kenney L., Merritt J., Adil R., Wu Q.-B., Zhen Y.-L., Morris R., Kreuzer J., Kathiresan M., Herrera Lopez X.I., Ellis H., Gritti I.G., Lecorgne L., Farag I., Popa A., Shen W., Kato H., Xu Q., Balasooriya E.R., Wu M.-J., Chaturantabut S., Kelley R.K., Cleary J.M., Lawrence M.S., Root D.E., Benes C.H., Deshpande V., Juric D., Sellers W.R., Ferrone C.R., Haas W., Vazquez F., Getz G., Bardeesy N.M.
Generation of a biliary tract cancer cell line atlas reveals molecular subtypes and therapeutic targets.
bioRxiv 2024:07.04.601970-07.04.601970(2024)

Cross-references
Cell line databases/resources DepMap; ACH-001961
Entry history
Entry creation19-Dec-2024
Last entry update19-Dec-2024
Version number1