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Cellosaurus CCX.E10 (CVCL_E4II)

[Text version]
Cell line name CCX.E10
Accession CVCL_E4II
Resource Identification Initiative To cite this cell line use: CCX.E10 (RRID:CVCL_E4II)
Comments Group: Bird cell line.
Group: Serum/protein free medium cell line.
Group: Vaccine production cell line.
From: Nuvonis Technologies GmbH; Vienna; Austria.
Biotechnology: Can be used for the manufacturing of the fusogenic oncolytic virus, rVSV-NDV, a recombinant vesicular stomatitis virus (VSV) backbone with fusogenic mutant glycoproteins of Newcastle disease virus (NDV) (PubMed=37584190).
Characteristics: Grows in suspension (Nuvonis).
Virology: When infected with Newcastle disease virus (NDV) produces high viral titers (CelloPub=CLPUB00780).
Doubling time: 0.8-1 day (Nuvonis).
Miscellaneous: Age at sampling from personal communication of Seipelt, Joachim.
Derived from site: In situ; Whole embryo; UBERON=UBERON_0000922.
Species of origin Coturnix japonica (Japanese quail) (Coturnix coturnix japonica) (NCBI Taxonomy: 93934)
Originate from same individual CVCL_E4IH ! CCX.2C4
Sex of cell Sex unspecified
Age at sampling 12FD
Category Spontaneously immortalized cell line
Web pages Provider; Nuvonis; -; https://nuvonis.com/ccx-cell-line/
Publications

CLPUB00780
Jug H., Hosta N., Tajnik Sbaizero M., Strancar A., Brodesser D.M., Tisch B., Heger T., Wolschek M., Seipelt J., Reiter M.
Production and purification of Newcastle disease virus.
BioProcess Int. 21:17-20(2023)

PubMed=37584190; DOI=10.1002/bit.28530
Gobel S., Jaen K.E., Fernandes R.P., Reiter M., Altomonte J., Reichl U., Genzel Y.
Characterization of a quail suspension cell line for production of a fusogenic oncolytic virus.
Biotechnol. Bioeng. 120:3335-3346(2023)

Entry history
Entry creation19-Dec-2024
Last entry update10-Apr-2025
Version number2