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Cellosaurus CHO-DXB11 5E27 (CVCL_E4IB)

[Text version]
Cell line name CHO-DXB11 5E27
Synonyms 5E27
Accession CVCL_E4IB
Resource Identification Initiative To cite this cell line use: CHO-DXB11 5E27 (RRID:CVCL_E4IB)
Comments Genetic integration: Method=Transfection; Gene=HGNC; HGNC:6019; IL6R (Note=With p.Phe345_Arg468del = sIL-6R).
Genetic integration: Method=Transfection; Gene=MGI; MGI:94890; Dhfr.
Transformant: ChEBI; CHEBI_23994; Ethyl methanesulfonate (Methylsulfonic acid ethyl ester; MSEE).
Transformant: NCIt; C44386; Gamma radiation.
Derived from site: In situ; Ovary; UBERON=UBERON_0000992.
Cell type: Epithelial cell of ovary; CL=CL_2000064.
Sequence variations
  • Gene deletion; UniProtKB; Q2MH30; Dhfr; Zygosity=Heterozygous (from parent cell line).
  • Mutation; UniProtKB; Q2MH30; Dhfr; Simple; p.Thr137Arg (c.410G>C); Zygosity=Heterozygous (from parent cell line).
Species of origin Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus) (NCBI Taxonomy: 10029)
Hierarchy Parent: CVCL_1977 (CHO-DXB11)
Sex of cell Female
Age at sampling Adult
Category Transformed cell line
Publications

PubMed=2292596; DOI=10.1093/oxfordjournals.jbchem.a123261
Yasukawa K., Saito T., Fukunaga T., Sekimori Y., Koishihara Y., Fukui H., Ohsugi Y., Matsuda T., Yawata H., Hirano T., Taga T., Kishimoto T.
Purification and characterization of soluble human IL-6 receptor expressed in CHO cells.
J. Biochem. 108:673-676(1990)

Entry history
Entry creation19-Dec-2024
Last entry update19-Dec-2024
Version number1