ID   CHO NA4-4
AC   CVCL_E4I6
SY   NA4-4; NA
RX   PubMed=2157974;
RX   PubMed=2243084;
CC   Sequence variation: Gene deletion; UniProtKB; Q2MH30; Dhfr; Zygosity=Heterozygous (from parent cell line).
CC   Sequence variation: Mutation; UniProtKB; Q2MH30; Dhfr; Simple; p.Thr137Arg (c.410G>C); Zygosity=Heterozygous (from parent cell line).
CC   Genetic integration: Method=Transfection; Gene=MGI; MGI:95824; Nr3c1 (Note=With p.Glu555Gly).
CC   Genetic integration: Method=Transfection; Gene=MGI; MGI:94890; Dhfr.
CC   Transformant: ChEBI; CHEBI_23994; Ethyl methanesulfonate (Methylsulfonic acid ethyl ester; MSEE).
CC   Transformant: NCIt; C44386; Gamma radiation.
CC   Derived from site: In situ; Ovary; UBERON=UBERON_0000992.
CC   Cell type: Epithelial cell of ovary; CL=CL_2000064.
OX   NCBI_TaxID=10029; ! Cricetulus griseus (Chinese hamster)
HI   CVCL_1977 ! CHO-DXB11
SX   Female
AG   Adult
CA   Transformed cell line
DT   Created: 19-12-24; Last updated: 19-12-24; Version: 1
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RX   PubMed=2157974; DOI=10.1210/mend-4-1-162;
RA   Hirst M.A., Northrop J.P., Danielsen M., Ringold G.M.;
RT   "High level expression of wild type and variant mouse glucocorticoid
RT   receptors in Chinese hamster ovary cells.";
RL   Mol. Endocrinol. 4:162-170(1990).
//
RX   PubMed=2243084; DOI=10.1016/S0021-9258(17)30478-7;
RA   Sanchez E.R., Hirst M.A., Scherrer L.C., Tang H.-Y., Welsh M.J.,
RA   Harmon J.M., Simons S.S. Jr., Ringold G.M., Pratt W.B.;
RT   "Hormone-free mouse glucocorticoid receptors overexpressed in Chinese
RT   hamster ovary cells are localized to the nucleus and are associated
RT   with both hsp70 and hsp90.";
RL   J. Biol. Chem. 265:20123-20130(1990).
//