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Cellosaurus CHO.IAR-4 (CVCL_E4I5)

[Text version]
Cell line name CHO.IAR-4
Synonyms CHO.IAR
Accession CVCL_E4I5
Resource Identification Initiative To cite this cell line use: CHO.IAR-4 (RRID:CVCL_E4I5)
Comments Characteristics: Transfected with a hybrid human insulin receptor (INSR), bacterial aspartate receptor (tar) construct (PubMed=3022282).
Genetic integration: Method=Transfection; Gene=HGNC; HGNC:6091; INSR (Note=With p.Asp949_Ser1382del).
Genetic integration: Method=Transfection; Gene=UniProtKB; P02941; Salmonella typhimurium methyl-accepting chemotaxis protein II (tar) (Note=With p.Met1_Arg170del).
Genetic integration: Method=Transfection; Gene=UniProtKB; P00552; Transposon Tn5 neo.
Derived from site: In situ; Ovary; UBERON=UBERON_0000992.
Cell type: Epithelial cell of ovary; CL=CL_2000064.
Species of origin Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus) (NCBI Taxonomy: 10029)
Hierarchy Parent: CVCL_0213 (CHO)
Sex of cell Female
Age at sampling Adult
Category Spontaneously immortalized cell line
Publications

PubMed=3022282; DOI=10.1073/pnas.83.21.8137; PMCID=PMC386882
Ellis L., Morgan D.O., Koshland D.E. Jr., Clauser E., Moe G.R., Bollag G., Roth R.A., Rutter W.J.
Linking functional domains of the human insulin receptor with the bacterial aspartate receptor.
Proc. Natl. Acad. Sci. U.S.A. 83:8137-8141(1986)

Entry history
Entry creation19-Dec-2024
Last entry update19-Dec-2024
Version number1