ID   CHO E-10B
AC   CVCL_E4HM
SY   E-10B
RX   Patent=EP0088540A2;
RX   Patent=US5004689;
RX   PubMed=6308636;
CC   Group: Patented cell line.
CC   Sequence variation: Gene deletion; UniProtKB; Q2MH30; Dhfr; Zygosity=Heterozygous (from parent cell line).
CC   Sequence variation: Mutation; UniProtKB; Q2MH30; Dhfr; Simple; p.Thr137Arg (c.410G>C); Zygosity=Heterozygous (from parent cell line).
CC   Genetic integration: Method=Transfection; Gene=HGNC; HGNC:5438; IFNG.
CC   Genetic integration: Method=Transfection; Gene=MGI; MGI:94890; Dhfr.
CC   Transformant: ChEBI; CHEBI_23994; Ethyl methanesulfonate (Methylsulfonic acid ethyl ester; MSEE).
CC   Transformant: NCIt; C44386; Gamma radiation.
CC   Derived from site: In situ; Ovary; UBERON=UBERON_0000992.
CC   Cell type: Epithelial cell of ovary; CL=CL_2000064.
OX   NCBI_TaxID=10029; ! Cricetulus griseus (Chinese hamster)
HI   CVCL_1977 ! CHO-DXB11
SX   Female
AG   Adult
CA   Transformed cell line
DT   Created: 19-12-24; Last updated: 19-12-24; Version: 1
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RX   Patent=EP0088540A2;
RA   Fiers W.C.;
RT   "DNA sequences, recombinant DNA molecules and processes for producing
RT   human immune interferon-like polypeptides.";
RL   Patent number EP0088540A2, 14-Sep-1983.
//
RX   Patent=US5004689;
RA   Fiers W.C., Allet B.;
RT   "DNA sequences, recombinant DNA molecules and processes for producing
RT   human gamma interferon-like polypeptides in high yields.";
RL   Patent number US5004689, 02-Apr-1991.
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RX   PubMed=6308636; DOI=10.1073/pnas.80.15.4654; PMCID=PMC384102;
RA   Scahill S.J., Devos R., Van der Heyden J., Fiers W.C.;
RT   "Expression and characterization of the product of a human immune
RT   interferon cDNA gene in Chinese hamster ovary cells.";
RL   Proc. Natl. Acad. Sci. U.S.A. 80:4654-4658(1983).
//