Cellosaurus cell line MGH138 (CVCL

Entry history
Cell line name	MGH138
Accession	CVCL_E4DQ
Resource Identification Initiative	To cite this cell line use: MGH138 (RRID:CVCL_E4DQ)
Comments	Characteristics: Erlotinib and gefitinib resistant (PubMed=26828195). Omics: Transcriptome analysis by microarray. Derived from site: Metastatic; Pleural effusion; UBERON=UBERON_0000175.
Sequence variations	Mutation; HGNC; HGNC:3236; EGFR; Unexplicit; Ex19del; Zygosity=Unspecified (PubMed=26828195). Mutation; HGNC; HGNC:3236; EGFR; Simple; p.Thr790Met (c.2369C>T); ClinVar=VCV000016613; Zygosity=Unspecified (PubMed=26828195).
Disease	Lung non-small cell carcinoma (NCIt: C2926)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell	Sex unspecified
Age at sampling	Age unspecified
Category	Cancer cell line
Publications	PubMed=26828195; DOI=10.1038/nm.4040; PMCID=PMC4900892 Hata A.N., Niederst M.J., Archibald H.L., Gomez-Caraballo M., Siddiqui F.M., Mulvey H.E., Maruvka Y.E., Ji F., Bhang H.-e.C., Krishnamurthy Radhakrishna V., Siravegna G., Hu H.-C., Raoof S., Lockerman E.L., Kalsy A., Lee D., Keating C.L., Ruddy D.A., Damon L.J., Crystal A.S., Costa C., Piotrowska Z., Bardelli A., Iafrate A.J., Sadreyev R.I., Stegmeier F., Getz G., Sequist L.V., Faber A.C., Engelman J.A. Tumor cells can follow distinct evolutionary paths to become resistant to epidermal growth factor receptor inhibition. Nat. Med. 22:262-269(2016)
Entry creation	19-Dec-2024
Last entry update	19-Dec-2024
Version number	1