| Cell line name |
PC9/3-14 |
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| Accession |
CVCL_E4DE |
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| Resource Identification Initiative |
To cite this cell line use: PC9/3-14 (RRID:CVCL_E4DE) |
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| Comments |
Population: Chinese; Han and Japanese.
Derived from site: Metastatic; Lymph node; UBERON=UBERON_0000029. |
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| Sequence variations |
- Mutation; HGNC; HGNC:3236; EGFR; Simple; p.Glu746_Ala750del (c.2235_2249del15); ClinVar=VCV000163343; Zygosity=Unspecified (from parent cell line).
- Mutation; HGNC; HGNC:3236; EGFR; Simple_edited; p.Thr790Met (c.2369C>T); ClinVar=VCV000016613; Zygosity=Heterozygous; Note=By CRISPR/Cas9 (PubMed=28422737).
- Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg248Gln (c.743G>A); ClinVar=VCV000012356; Zygosity=Homozygous (from parent cell line).
|
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| Disease |
Lung adenocarcinoma (NCIt: C3512) |
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| Species of origin |
Homo sapiens (Human)
(NCBI Taxonomy: 9606) |
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| Hierarchy |
Parent: CVCL_B260 (PC-9) |
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| Sex of cell |
Male |
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| Age at sampling |
45Y |
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| Category |
Cancer cell line |
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| Publications | PubMed=28422737; DOI=10.18632/oncotarget.16752; PMCID=PMC5482658
Park M.-Y., Jung M.H., Eo E.Y., Kim S., Lee S.H., Lee Y.J., Park J.S., Cho Y.J., Chung J.H., Kim C.H., Yoon H.I., Lee J.H., Lee C.-T.
Generation of lung cancer cell lines harboring EGFR T790M mutation by CRISPR/Cas9-mediated genome editing.
Oncotarget 8:36331-36338(2017) |
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| Entry history |
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| Entry creation | 19-Dec-2024 |
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| Last entry update | 19-Dec-2024 |
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| Version number | 1 |
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