ID   GCT-C
AC   CVCL_E4CX
SY   UR-HCL-1 clone A
RX   PubMed=304748;
CC   Population: Caucasian.
CC   Sequence variation: Mutation; HGNC; HGNC:1097; BRAF; Simple; p.Val600Glu (c.1799T>A); ClinVar=VCV000013961; Zygosity=Heterozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; HGNC:1787; CDKN2A; Simple; p.Leu32Arg (c.95_96TG>GT); Zygosity=Homozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg248Trp (c.742C>T); ClinVar=VCV000012347; Zygosity=Heterozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; HGNC:11998; TP53; Simple; p.Gln317Ter (c.948_949delinsTT) (c.948_949CC>TT); Zygosity=Heterozygous (from parent cell line).
CC   Derived from site: Metastatic; Lung; UBERON=UBERON_0002048.
DI   NCIt; C4247; Undifferentiated pleomorphic sarcoma
DI   ORDO; Orphanet_2023; Undifferentiated pleomorphic sarcoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_1229 ! GCT
SX   Male
AG   29Y
CA   Cancer cell line
DT   Created: 19-12-24; Last updated: 19-12-24; Version: 1
//
RX   PubMed=304748; DOI=10.1182/blood.V51.3.507.507;
RA   DiPersio J.F., Brennan J.K., Lichtman M.A., Speiser B.L.;
RT   "Human cell lines that elaborate colon-stimulating activity for the
RT   marrow cells of man and other species.";
RL   Blood 51:507-519(1978).
//