ID   EYQ2-20
AC   CVCL_E4CE
RX   PubMed=33558651;
RX   PubMed=36202854;
CC   Knockout cell: Method=CRISPR/Cas9; HGNC; HGNC:14294; SHANK3 (Note=1 of 2 alleles).
CC   Derived from site: In situ; Blastocyst; UBERON=UBERON_0000358.
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_9773 ! WA09
SX   Female
AG   Blastocyst stage
CA   Embryonic stem cell
DT   Created: 19-12-24; Last updated: 19-12-24; Version: 1
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RX   PubMed=33558651; DOI=10.1038/s41380-021-01023-2; PMCID=PMC8349370;
RA   Chiola S., Napan K.L., Wang Y.-Q., Lazarenko R.M., Armstrong C.J.,
RA   Cui J., Shcheglovitov A.;
RT   "Defective AMPA-mediated synaptic transmission and morphology in human
RT   neurons with hemizygous SHANK3 deletion engrafted in mouse prefrontal
RT   cortex.";
RL   Mol. Psychiatry 26:4670-4686(2021).
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RX   PubMed=36202854; DOI=10.1038/s41467-022-33364-z; PMCID=PMC9537523;
RA   Wang Y.-Q., Chiola S., Yang G., Russell C., Armstrong C.J., Wu Y.-Y.,
RA   Spampanato J.G., Tarboton P., Ullah H.M.A., Edgar N.U., Chang A.N.,
RA   Harmin D.A., Bocchi V.D., Vezzoli E., Besusso D., Cui J., Cattaneo E.,
RA   Kubanek J., Shcheglovitov A.;
RT   "Modeling human telencephalic development and autism-associated SHANK3
RT   deficiency using organoids generated from single neural rosettes.";
RL   Nat. Commun. 13:5688.1-5688.25(2022).
//