Cellosaurus K562-Fluc-Puro/HuBCMA-Neo (CVCL_E4BI)
| Cell line name | K562-Fluc-Puro/HuBCMA-Neo |
|---|---|
| Accession | CVCL_E4BI |
| Resource Identification Initiative | To cite this cell line use: K562-Fluc-Puro/HuBCMA-Neo (RRID:CVCL_E4BI) |
| Comments | Population: Caucasian. Characteristics: Reporter cell line, transduced with the LV-Fluc-P2A-PuroR vector encoding for luciferase linked via a P2A cleavage peptide to the PuroR gene and under control of the spleen focus-forming virus (SFFV) promoter (from parent cell line). Characteristics: Transduced with a human TNFRS17/BCMA and neo encoding lentivirus (Imanis=CL192). Genetic integration: Method=Transduction; Gene=HGNC; HGNC:11913; TNFRSF17. Genetic integration: Method=Transduction; Gene=UniProtKB; P08659; Firefly luciferase. Genetic integration: Method=Transduction; Gene=UniProtKB; P13249; S.alboniger pac (PuroR). Genetic integration: Method=Transduction; Gene=UniProtKB; P00552; Transposon Tn5 neo. Derived from site: In situ; Pleural effusion; UBERON=UBERON_0000175. |
| Sequence variations |
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| Disease | Blast phase chronic myelogenous leukemia, BCR-ABL1 positive (NCIt: C9110) Chronic myeloid leukemia (ORDO: Orphanet_521) |
| Species of origin | Homo sapiens (Human) (NCBI Taxonomy: 9606) |
| Hierarchy | Parent: CVCL_D5KI (K562-Fluc-Puro) |
| Sex of cell | Female |
| Age at sampling | 53Y |
| Category | Cancer cell line |
| Cross-references | |
| Cell line collections (Providers) | Imanis; CL192 |
| Entry history | |
| Entry creation | 19-Dec-2024 |
| Last entry update | 10-Apr-2025 |
| Version number | 2 |