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Cellosaurus MEF Lrrk2-p.R1441C KI (CVCL_E3XD)

[Text version]
Cell line name MEF Lrrk2-p.R1441C KI
Synonyms MEF Lrrk2 R1441C knock-in
Accession CVCL_E3XD
Resource Identification Initiative To cite this cell line use: MEF Lrrk2-p.R1441C KI (RRID:CVCL_E3XD)
Comments Genetic integration: Method=Transduction; Gene=UniProtKB; P03070; SV40 large T antigen.
Genetic integration: Method=Transduction; Gene=UniProtKB; P00557; Escherichia coli hygromycin-B 4-O-kinase (hph) (HygR).
Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40).
Miscellaneous: Cell line information from personal communication of Tonelli, Francesca.
Derived from site: In situ; Whole embryo; UBERON=UBERON_0000922.
Cell type: Fibroblast; CL=CL_0000057.
Sequence variations
  • Mutation; MGI; MGI:1913975; Lrrk2; Simple_edited; p.Arg1441Cys (c.4321C>T); Zygosity=Homozygous; Note=By targeting vector (JAX).
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: B6.Cg-Lrrk2tm1.1Shn/J (IMSR_JAX:009346).
Sex of cell Sex unspecified
Age at sampling 12-13FD
Category Transformed cell line
Entry history
Entry creation19-Dec-2024
Last entry update19-Dec-2024
Version number1