Cellosaurus cell line CSBZZUi001-A (CVCL

Cross-references
Cell line name	CSBZZUi001-A
Synonyms	CSBZZU_PS1_001
Accession	CVCL_E3TU
Resource Identification Initiative	To cite this cell line use: CSBZZUi001-A (RRID:CVCL_E3TU)
Comments	From: The first affiliated Hospital of Zhengzhou University; Zhengzhou; China. Population: Chinese; Han. Derived from site: In situ; Skin; UBERON=UBERON_0002097. Cell type: Fibroblast of skin; CL=CL_0002620.
Sequence variations	Mutation; HGNC; HGNC:9508; PSEN1; Simple; p.Phe237Leu (c.709T>C); ClinVar=VCV000098072; Zygosity=Heterozygous (PubMed=38968760).
Disease	Alzheimer's disease 3 (NCIt: C123412) Early-onset autosomal dominant Alzheimer disease (ORDO: Orphanet_1020)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell	Female
Age at sampling	46Y
Category	Induced pluripotent stem cell
Publications	PubMed=38968760; DOI=10.1016/j.scr.2024.103486 Meng X.-Y., Sun H.-F., Zhang Y.-J., Li W.-X., Wang D.-D., Liu D.-H., Li S.-M., Wu Y., Li J.-K., Liu X.-H., Liu P.-P., Yang R.-Z., Li S.-A., Kang J.-S. Generation of an induced pluripotent stem cell line (CSBZZUi001-A) from a female Alzheimer's patient carrying the PSEN1 709 T > C heterozygous mutation. Stem Cell Res. 79:103486-103486(2024)
Cell line databases/resources	hPSCreg; CSBZZUi001-A
Biological sample resources	BioSamples; SAMEA115444276
Entry history
Entry creation	19-Dec-2024
Last entry update	19-Dec-2024
Version number	1