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Cellosaurus UMANe002-A-4 (CVCL_E3RS)

[Text version]
Cell line name UMANe002-A-4
Synonyms IBM13-19; UMANCe003-A-4
Accession CVCL_E3RS
Resource Identification Initiative To cite this cell line use: UMANe002-A-4 (RRID:CVCL_E3RS)
Comments Population: Caucasian.
Knockout cell: Method=CRISPR/Cas9; HGNC; HGNC:11630; HNF1B (Note=1 of 2 alleles).
Derived from site: In situ; Blastocyst; UBERON=UBERON_0000358.
Cell type: Embryonic stem cell; CL=CL_0002322.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_L201 (Man-13)
Sex of cell Male
Age at sampling Blastocyst stage
Category Embryonic stem cell
Publications

PubMed=38788724; DOI=10.1016/j.stemcr.2024.04.011; PMCID=PMC11297557
Bantounas I., Rooney K.M., Lopes F.M., Tengku F., Woods S., Zeef L.A.H., Lin I.-H., Kuba S.Y., Bates N., Hummelgaard S., Hillman K.A., Cereghini S., Woolf A.S., Kimber S.J.
Human pluripotent stem cell-derived kidney organoids reveal tubular epithelial pathobiology of heterozygous HNF1B-associated dysplastic kidney malformations.
Stem Cell Reports 19:859-876(2024)

Cross-references
Cell line databases/resources hPSCreg; UMANe002-A-4
Biological sample resources BioSamples; SAMEA115495030
Entry history
Entry creation19-Dec-2024
Last entry update19-Dec-2024
Version number1