ID   HS5-CD40L
AC   CVCL_E3RF
RX   PubMed=38877102;
CC   Population: Caucasian.
CC   Genetic integration: Method=Transduction; Gene=HGNC; HGNC:11935; CD40LG.
CC   Genetic integration: Method=Transduction; Gene=UniProtKB; P03126; Human papillomavirus type 16 protein E6.
CC   Genetic integration: Method=Transduction; Gene=UniProtKB; P03129; Human papillomavirus type 16 protein E7.
CC   Genetic integration: Method=Transduction; Gene=UniProtKB; P33967; B.cereus Bsr.
CC   Genetic integration: Method=Transduction; Gene=UniProtKB; P00552; Transposon Tn5 neo.
CC   Transformant: NCBI_TaxID; 333760; Human papillomavirus type 16 (HPV16).
CC   Derived from site: In situ; Bone marrow, stroma; UBERON=UBERON_0007195.
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_3720 ! HS-5
SX   Male
AG   30Y
CA   Transformed cell line
DT   Created: 19-12-24; Last updated: 19-12-24; Version: 1
//
RX   PubMed=38877102; DOI=10.1038/s41375-024-02284-w; PMCID=PMC11286525;
RA   Hoferkova E., Seda V., Kadakova S., Verner J., Loja T., Matulova K.,
RA   Skuhrova Francova H., Ondrouskova E., Filip D., Blavet N., Boudny M.,
RA   Mladonicka Pavlasova G., Vecera J., Ondrisova L., Pavelkova P.,
RA   Hlavac K., Kostalova L., Michaelou A., Pospisilova S., Dorazilova J.,
RA   Chochola V., Jaros J., Doubek M., Jarosova M., Hampl A., Vojtova L.,
RA   Kren L., Mayer J., Mraz M.;
RT   "Stromal cells engineered to express T cell factors induce robust CLL
RT   cell proliferation in vitro and in PDX co-transplantations allowing
RT   the identification of RAF inhibitors as anti-proliferative drugs.";
RL   Leukemia 38:1699-1711(2024).
//