Cellosaurus logo
expasy logo

Cellosaurus RBL-IV HR+ (CVCL_E3P7)

[Text version]
Cell line name RBL-IV HR+
Synonyms RBL-HR+; AB-CBF1-MCT-1; MCT-1
Accession CVCL_E3P7
Resource Identification Initiative To cite this cell line use: RBL-IV HR+ (RRID:CVCL_E3P7)
Comments Problematic cell line: Misidentified/contaminated. Originally thought to be a mouse cell line, but later found to be derivative of RBL-IV (PubMed=102698; PubMed=6166481).
Transformant: ChEBI; CHEBI_232042; Beta-chloro-N-isopropyl-2-naphthaleneethanamine hydrochloride (ICI 42464).
Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
Cell type: Basophil; CL=CL_0000767.
Disease Rat leukemia (NCIt: C60428)
Species of origin Rattus norvegicus (Rat) (NCBI Taxonomy: 10116)
Breed/subspecies: Wistar; RS=RS:0000955.
Hierarchy Parent: CVCL_E3P6 (RBL-IV)
Children:
CVCL_0591 (RBL-2H3)
Category Cancer cell line
Publications

PubMed=72105; DOI=10.4049/jimmunol.119.5.1757
Taurog J.D., Mendoza G.R., Hook W.A., Siraganian R.P., Metzger H.
Noncytotoxic IgE-mediated release of histamine and serotonin from murine mastocytoma cells.
J. Immunol. 119:1757-1761(1977)

PubMed=102698; DOI=10.4049/jimmunol.121.6.2584
Siraganian R.P., Metzger H.
Evidence that the 'mouse mastocytoma' cell line (MCT-1) is of rat origin.
J. Immunol. 121:2584-2585(1978)

PubMed=6166481; DOI=10.1002/eji.1830110410
Barsumian E.L., Isersky C., Petrino M.G., Siraganian R.P.
IgE-induced histamine release from rat basophilic leukemia cell lines: isolation of releasing and nonreleasing clones.
Eur. J. Immunol. 11:317-323(1981)

PubMed=19669619; DOI=10.1007/s00011-009-0074-y
Passante E., Frankish N.
The RBL-2H3 cell line: its provenance and suitability as a model for the mast cell.
Inflamm. Res. 58:737-745(2009)

Entry history
Entry creation19-Dec-2024
Last entry update19-Dec-2024
Version number1