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Cellosaurus MCF10A-KRAS-b_type-10 (CVCL_E3JS)

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Cell line name MCF10A-KRAS-b_type-10
Synonyms 06M00013
Accession CVCL_E3JS
Resource Identification Initiative To cite this cell line use: MCF10A-KRAS-b_type-10 (RRID:CVCL_E3JS)
Comments Part of: Fukushima Translational Research Project gene-overexpressing cell lines panel.
Genetic integration: Method=Transduction; Gene=HGNC; HGNC:6407; KRAS (Note=With p.Gln61Leu (c.182A>T)).
Genetic integration: Method=Transduction; Gene=UniProtKB; P00557; Escherichia coli hygromycin-B 4-O-kinase (hph) (HygR).
Derived from site: In situ; Breast, epithelium; UBERON=UBERON_0008367.
Sequence variations
  • Gene deletion; HGNC; HGNC:1787; CDKN2A; Zygosity=Homozygous (from parent cell line).
  • Gene deletion; HGNC; HGNC:1788; CDKN2B; Zygosity=Homozygous (from parent cell line).
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0598 (MCF-10A)
Sex of cell Female
Age at sampling 36Y
Category Spontaneously immortalized cell line
Web pages https://www.fmu.ac.jp/home/trc/en/contract-research-provision/human-gene-overexpressing-cell-lines/
Entry history
Entry creation19-Dec-2024
Last entry update19-Dec-2024
Version number1