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Cellosaurus HyCyte NCI-H157-Luc (CVCL_E3I3)

[Text version]
Cell line name HyCyte NCI-H157-Luc
Synonyms Luciferase Reporter NCI-H157 Cell Line
Accession CVCL_E3I3
Resource Identification Initiative To cite this cell line use: HyCyte NCI-H157-Luc (RRID:CVCL_E3I3)
Comments Problematic cell line: Contaminated. Parent cell line (NCI-H157) has been shown to be identical to NCI-H1264.
Doubling time: 24-48 hours (Hysigen=TCH-C431L).
Genetic integration: Method=Transduction; Gene=UniProtKB; P08659; Firefly luciferase.
Genetic integration: Method=Transduction; Gene=UniProtKB; P13249; S.alboniger pac (PuroR).
Sequence variations
  • Mutation; HGNC; HGNC:1787; CDKN2A; Simple; p.His83Tyr (c.247C>T) (p.Ala97Val, c.290C>T); ClinVar=VCV000376307; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; HGNC:6407; KRAS; Simple; p.Gly12Arg (c.34G>C); ClinVar=VCV000012579; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Leu35Phefs*8 (c.102_103insT) (c.103_104insT); Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Glu298Ter (c.892G>T); ClinVar=VCV000093323; Zygosity=Heterozygous (from parent cell line).
Disease Lung squamous cell carcinoma (NCIt: C3493)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0463 (NCI-H157)
Sex of cell Male
Age at sampling 59Y
Category Cancer cell line
Cross-references
Cell line collections (Providers) Hysigen; TCH-C431L
Entry history
Entry creation19-Dec-2024
Last entry update19-Dec-2024
Version number1