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Cellosaurus HyCyte HL-60-Luc-GFP (CVCL_E3HJ)

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Cell line name HyCyte HL-60-Luc-GFP
Synonyms Luciferase/GFP Dual-Reporter HL-60 Cell Line
Accession CVCL_E3HJ
Resource Identification Initiative To cite this cell line use: HyCyte HL-60-Luc-GFP (RRID:CVCL_E3HJ)
Comments Population: Caucasian.
Doubling time: 36-48 hours (Hysigen=TCH-C204LG).
Genetic integration: Method=PiggyBac transposition; Gene=FPbase; R9NL8; eGFP (Note=Enhanced GFP).
Genetic integration: Method=PiggyBac transposition; Gene=UniProtKB; P08659; Firefly luciferase.
Genetic integration: Method=PiggyBac transposition; Gene=UniProtKB; P13249; S.alboniger pac (PuroR).
Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
Sequence variations
  • Gene deletion; HGNC; HGNC:11998; TP53; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; HGNC:1787; CDKN2A; Simple; p.Arg80Ter (c.238C>T) (p.Pro94Leu, c.281C>T); ClinVar=VCV000009409; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; HGNC:7989; NRAS; Simple; p.Gln61Leu (c.182A>T); ClinVar=VCV000375874; Zygosity=Heterozygous (from parent cell line).
Disease Adult acute myeloid leukemia (NCIt: C9154)
Acute myeloid leukemia (ORDO: Orphanet_519)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0002 (HL-60)
Sex of cell Female
Age at sampling 36Y
Category Cancer cell line
Cross-references
Cell line collections (Providers) Hysigen; TCH-C204LG
Entry history
Entry creation19-Dec-2024
Last entry update19-Dec-2024
Version number1