| Cell line name |
HyCyte HCT 15-Luc |
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| Synonyms |
Luciferase Reporter HCT 15 Cell Line |
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| Accession |
CVCL_E3HC |
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| Resource Identification Initiative |
To cite this cell line use: HyCyte HCT 15-Luc (RRID:CVCL_E3HC) |
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| Comments |
Population: Caucasian.
Doubling time: 24-48 hours (Hysigen=TCH-C186L).
Genetic integration: Method=Transduction; Gene=UniProtKB; P08659; Firefly luciferase.
Genetic integration: Method=Transduction; Gene=UniProtKB; P13249; S.alboniger pac (PuroR).
Derived from site: In situ; Colon; UBERON=UBERON_0001155.
Cell type: Epithelial cell of colon; CL=CL_0011108. |
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| Sequence variations |
- Mutation; HGNC; HGNC:583; APC; Simple; p.Arg727Met (c.2180G>T); Zygosity=Heterozygous (from parent cell line).
- Mutation; HGNC; HGNC:583; APC; Simple; p.Lys993Asn (c.2979G>T); Zygosity=Heterozygous (from parent cell line).
- Mutation; HGNC; HGNC:583; APC; Simple; p.Ile1417Leufs*2 (c.4248delC); Zygosity=Heterozygous (from parent cell line).
- Mutation; HGNC; HGNC:583; APC; Simple; p.Arg2166Ter (c.6496C>T); ClinVar=VCV000438883; Zygosity=Heterozygous (from parent cell line).
- Mutation; HGNC; HGNC:914; B2M; Simple; c.68-1G>T; Zygosity=Heterozygous; Note=Splice acceptor mutation (from parent cell line).
- Mutation; HGNC; HGNC:914; B2M; Simple; p.Tyr30Ter (c.90C>A); Zygosity=Heterozygous (from parent cell line).
- Mutation; HGNC; HGNC:1101; BRCA2; Simple; p.Cys1200Terfs (c.3599_3600delGT) (3827delGT); Zygosity=Heterozygous (from parent cell line).
- Mutation; HGNC; HGNC:1101; BRCA2; Simple; p.Asn1784Hisfs*7 (c.5350_5351delAA); ClinVar=VCV000037959; Zygosity=Heterozygous (from parent cell line).
- Mutation; HGNC; HGNC:16627; CHEK2; Simple; p.Arg145Trp (c.433C>T); ClinVar=VCV000005592; Zygosity=Heterozygous (from parent cell line).
- Mutation; HGNC; HGNC:6407; KRAS; Simple; p.Gly13Asp (c.38G>A); ClinVar=VCV000012580; Zygosity=Heterozygous (from parent cell line).
- Mutation; HGNC; HGNC:8975; PIK3CA; Simple; p.Glu545Lys (c.1633G>A); ClinVar=VCV000013655; Zygosity=Heterozygous (from parent cell line).
- Mutation; HGNC; HGNC:8975; PIK3CA; Simple; p.Asp549Asn (c.1645G>A); ClinVar=VCV000375900; Zygosity=Heterozygous (from parent cell line).
- Mutation; HGNC; HGNC:11998; TP53; Simple; p.Ser241Phe (c.722C>T); ClinVar=VCV000012359; Zygosity=Heterozygous (from parent cell line).
- Mutation; HGNC; HGNC:11998; TP53; Simple; c.1101-2A>C; ClinVar=VCV000635383; Zygosity=Heterozygous; Note=Splice acceptor mutation (from parent cell line).
|
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| Disease |
Colon adenocarcinoma (NCIt: C4349) |
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| Species of origin |
Homo sapiens (Human)
(NCBI Taxonomy: 9606) |
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| Hierarchy |
Parent: CVCL_0292 (HCT 15) |
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| Sex of cell |
Male |
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| Age at sampling |
67Y |
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| Category |
Cancer cell line |
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| Cross-references |
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| Cell line collections (Providers) |
Hysigen; TCH-C186L
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| Entry history |
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| Entry creation | 19-Dec-2024 |
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| Last entry update | 19-Dec-2024 |
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| Version number | 1 |
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