ID   HepG2-FVII
AC   CVCL_E3FN
SY   FVII-HepG2
RX   PubMed=31381603;
CC   Population: Caucasian.
CC   Sequence variation: Mutation; HGNC; HGNC:7989; NRAS; Simple; p.Gln61Leu (c.182A>T); ClinVar=VCV000375874; Zygosity=Heterozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; HGNC:11730; TERT; Simple; c.1-124C>T (c.228C>T) (C228T); Zygosity=Unspecified; Note=In promoter (from parent cell line).
CC   Genetic integration: Method=Transduction; Gene=HGNC; HGNC:3544; F7.
CC   Genetic integration: Method=Transduction; Gene=UniProtKB; P13249; S.alboniger pac (PuroR).
CC   Derived from site: In situ; Liver; UBERON=UBERON_0002107.
DI   NCIt; C3728; Hepatoblastoma
DI   ORDO; Orphanet_449; Hepatoblastoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_0027 ! Hep-G2
SX   Male
AG   15Y
CA   Cancer cell line
DT   Created: 19-12-24; Last updated: 19-12-24; Version: 1
//
RX   PubMed=31381603; DOI=10.1371/journal.pone.0220825; PMCID=PMC6681952;
RA   Pongjantarasatian S., Kadegasem P., Sasanakul W., Sa-ngiamsuntorn K.,
RA   Borwornpinyo S., Sirachainan N., Chuansumrit A., Tanratana P.,
RA   Hongeng S.;
RT   "Coagulant activity of recombinant human factor VII produced by
RT   lentiviral human F7 gene transfer in immortalized hepatocyte-like cell
RT   line.";
RL   PLoS ONE 14:E0220825-E0220825(2019).
//