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Cellosaurus 10101 (CVCL_E3EB)

[Text version]
Cell line name 10101
Accession CVCL_E3EB
Resource Identification Initiative To cite this cell line use: 10101 (RRID:CVCL_E3EB)
Comments Population: Caucasian, not Hispanic.
Doubling time: 42-48 hours (Direct_author_submission).
Miscellaneous: Cell line information from personal communication of Jenkins, Russell W.
Derived from site: Metastatic; Pelvis, hypodermis; UBERON=UBERON_0002355+UBERON_0002072.
Sequence variations
  • Mutation; HGNC; HGNC:583; APC; Simple; p.Ser2557Phe (c.7670C>T); ClinVar=VCV000827187; Zygosity=Unspecified (Direct_author_submission).
  • Mutation; HGNC; HGNC:795; ATM; Simple; c.5005+1G>A; ClinVar=VCV000859032; Zygosity=Unspecified; Note=Splice donor mutation (Direct_author_submission).
  • Mutation; HGNC; HGNC:1097; BRAF; Simple; p.Ser614Phe (c.1841C>T); Zygosity=Unspecified (Direct_author_submission).
  • Mutation; HGNC; HGNC:7029; MET; Simple; c.-14-1G>A; Zygosity=Unspecified (Direct_author_submission).
  • Mutation; HGNC; HGNC:7217; MPL; Simple; c.1565+5C>T; ClinVar=VCV000135564; Zygosity=Unspecified (Direct_author_submission).
  • Mutation; HGNC; HGNC:7989; NRAS; Simple; p.Gln61Leu (c.182A>T); ClinVar=VCV000375874; Zygosity=Unspecified (Direct_author_submission).
  • Mutation; HGNC; HGNC:11730; TERT; Simple; c.1-124C>T (c.228C>T) (C228T); Zygosity=Unspecified; Note=In promoter (Direct_author_submission).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Gln317Ter (c.949C>T); ClinVar=VCV000450344; Zygosity=Unspecified (Direct_author_submission).
  • Mutation; HGNC; HGNC:15979; TP63; Simple; p.Gln257Glu (c.769C>G); Zygosity=Unspecified (Direct_author_submission).
  • Mutation; HGNC; HGNC:12363; TSC2; Simple; p.His1135Tyr (c.3403C>T); ClinVar=VCV001442116; Zygosity=Unspecified (Direct_author_submission).
Disease Cutaneous melanoma (NCIt: C3510)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 78Y
Category Cancer cell line
Entry history
Entry creation19-Dec-2024
Last entry update19-Dec-2024
Version number1