Cellosaurus SK-OV-3/pVgRXR/pINDp53wt (CVCL_E3EA)
Cell line name | SK-OV-3/pVgRXR/pINDp53wt |
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Accession | CVCL_E3EA |
Resource Identification Initiative | To cite this cell line use: SK-OV-3/pVgRXR/pINDp53wt (RRID:CVCL_E3EA) |
Comments | Population: Caucasian. Characteristics: Transfected with the pVgRXR vector that contains the VgEcR fusion protein under the control of a CMV promoter and RXRA under the control of a RSV promoter as well as BleoR. Also transfected with pINDp53wt (PubMed=15755800). Genetic integration: Method=Transfection; Gene=HGNC; HGNC:10477; RXRA. Genetic integration: Method=Transfection; Gene=HGNC; HGNC:11998; TP53. Genetic integration: Method=Transfection; Gene=FlyBase_Gene; FBgn0000546; EcR (Note=With p.Met1_Val221del, as 2nd part of VgECR). Genetic integration: Method=Transfection; Gene=UniProtKB; P06492; Human herpesvirus 1 VP16 (UL28) (Note=With p.Met1_Thr412del, as 1st part of VgECR). Genetic integration: Method=Transfection; Gene=UniProtKB; P17493; Streptoalloteichus hindustanus ble (BleoR). Genetic integration: Method=Transfection; Gene=UniProtKB; P00552; Transposon Tn5 neo. Derived from site: Metastatic; Ascites; UBERON=UBERON_0007795. |
Sequence variations |
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Disease | Ovarian serous cystadenocarcinoma (NCIt: C7978) |
Species of origin | Homo sapiens (Human) (NCBI Taxonomy: 9606) |
Hierarchy | Parent: CVCL_E3E8 (SK-OV-3/pVgRXR) |
Sex of cell | Female |
Age at sampling | 64Y |
Category | Cancer cell line |
Publications | PubMed=15755800; DOI=10.1093/mutage/gei016 |
Entry history | |
Entry creation | 10-Sep-2024 |
Last entry update | 19-Dec-2024 |
Version number | 2 |