ID   GUMC-29
AC   CVCL_E3DN
RX   PubMed=28009986;
CC   Characteristics: Established by conditional reprogramming (CR), a cell culture method in which epithelial cells are seeded onto an irradiated 3T3-J2 mouse fibroblast feeder layer in a specialized medium that contains Y-276321 an inhibitor of ROCK1 and ROCK2 (PubMed=28009986).
CC   Characteristics: Obtained from the non-malignant tissue of the prostate cancer patient (PubMed=28009986).
CC   Sequence variation: Gene fusion; HGNC; 3446; ERG + HGNC; 11876; TMPRSS2; Name(s)=TMPRSS2-ERG (from autologous cell line RC-123T/E).
CC   Omics: Deep exome analysis.
CC   Omics: Transcriptome analysis by microarray.
CC   Derived from site: In situ; Prostate, epithelium; UBERON=UBERON_0000428.
CC   Cell type: Epithelial cell of prostate; CL=CL_0002231.
ST   Source(s): PubMed=28009986
ST   Amelogenin: X,Y
ST   CSF1PO: 10,12
ST   D13S317: 12,14
ST   D16S539: 11,12
ST   D18S51: 12,15
ST   D19S433: 14,17.2
ST   D21S11: 29,30
ST   D2S1338: 18,25
ST   D3S1358: 17,18
ST   D5S818: 9,12
ST   D7S820: 9,11
ST   D8S1179: 12,13
ST   FGA: 18,26
ST   TH01: 6,9.3
ST   TPOX: 9,11
ST   vWA: 14,17
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
OI   CVCL_E3DP ! GUMC-30
OI   CVCL_VV24 ! RC-123T/E
SX   Male
AG   57Y
CA   Spontaneously immortalized cell line
DT   Created: 10-09-24; Last updated: 10-09-24; Version: 1
//
RX   PubMed=28009986; DOI=10.18632/oncotarget.13937; PMCID=PMC5410259;
RA   Timofeeva O.A., Palechor-Ceron N., Li G.-L., Yuan H., Krawczyk E.,
RA   Zhong X.-G., Liu G., Upadhyay G., Dakic A., Yu S.-T., Fang S.-A.,
RA   Choudhury S., Zhang X.-P., Ju A., Lee M.-S., Dan H.C., Ji Y.-M., Hou Y.,
RA   Zheng Y.-L., Albanese C., Rhim J.S., Schlegel R., Dritschilo A.,
RA   Liu X.-F.;
RT   "Conditionally reprogrammed normal and primary tumor prostate
RT   epithelial cells: a novel patient-derived cell model for studies of
RT   human prostate cancer.";
RL   Oncotarget 8:22741-22758(2017).
//