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Cellosaurus Rat-1/T7-Cdt1 Cy CB4 (CVCL_E3DA)

[Text version]
Cell line name Rat-1/T7-Cdt1 Cy CB4
Accession CVCL_E3DA
Resource Identification Initiative To cite this cell line use: Rat-1/T7-Cdt1 Cy CB4 (RRID:CVCL_E3DA)
Comments Genetic integration: Method=Transduction; Gene=HGNC; HGNC:24576; CDT1 (Note=With mutated cyclin-binding motif and a N-terminal T7 tag).
Genetic integration: Method=Transduction; Gene=UniProtKB; P00557; Escherichia coli hygromycin-B 4-O-kinase (hph) (HygR).
Derived from site: In situ; Whole embryo; UBERON=UBERON_0000922.
Cell type: Fibroblast; CL=CL_0000057.
Species of origin Rattus norvegicus (Rat) (NCBI Taxonomy: 10116)
Breed/subspecies: Fischer 344; RS=RS:0000215.
Hierarchy Parent: CVCL_0492 (Rat1)
Sex of cell Sex unspecified
Age at sampling Embryo
Category Spontaneously immortalized cell line
Publications

PubMed=16835273; DOI=10.1242/jcs.03031
Tatsumi Y., Sugimoto N., Yugawa T., Narisawa-Saito M., Kiyono T., Fujita M.
Deregulation of Cdt1 induces chromosomal damage without rereplication and leads to chromosomal instability.
J. Cell Sci. 119:3128-3140(2006)

Entry history
Entry creation10-Sep-2024
Last entry update19-Dec-2024
Version number2