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Cellosaurus CaOV3 CBPR (CVCL_E3AS)

[Text version]
Cell line name CaOV3 CBPR
Accession CVCL_E3AS
Resource Identification Initiative To cite this cell line use: CaOV3 CBPR (RRID:CVCL_E3AS)
Comments Population: Caucasian.
Selected for resistance to: ChEBI; CHEBI:31355; Carboplatin (CBP; Paraplatin).
Omics: Metabolome analysis.
Derived from site: In situ; Ovary; UBERON=UBERON_0000992.
Sequence variations
  • Mutation; HGNC; 11998; TP53; Simple; p.Gln136Ter (c.406C>T); ClinVar=VCV001802458; Zygosity=Homozygous (from parent cell line).
Disease High grade ovarian serous adenocarcinoma (NCIt: C105555)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0201 (Caov-3)
Sex of cell Female
Age at sampling 54Y
Category Cancer cell line
Publications

PubMed=35681748; DOI=10.3390/cancers14112763; PMCID=PMC9179525
Acland M., Lokman N.A., Young C., Anderson D., Condina M.R., Desire C., Noye T.M., Wang W.-Q., Ricciardelli C., Creek D.J., Oehler M.K., Hoffmann P., Klingler-Hoffmann M.
Chemoresistant cancer cell lines are characterized by migratory, amino acid metabolism, protein catabolism and IFN1 signalling perturbations.
Cancers (Basel) 14:2763.1-2763.24(2022)

Entry history
Entry creation10-Sep-2024
Last entry update10-Sep-2024
Version number1