• Gene deletion; HGNC; HGNC:1787; CDKN2A; Zygosity=Homozygous (PubMed=15495191; PubMed=18487078).
  
• Mutation; HGNC; HGNC:11998; TP53; Simple; p.Leu26Profs*10 (c.75delA); Zygosity=Unspecified (PubMed=10628319; PubMed=18487078).
  

PubMed=10628319
Ballo H., Koldovsky P., Hoffmann T.K., Balz V., Hildebrandt B., Gerharz C.-D., Bier H.
Establishment and characterization of four cell lines derived from human head and neck squamous cell carcinomas for an autologous tumor-fibroblast in vitro model.
Anticancer Res. 19:3827-3836(1999)

PubMed=15495191; DOI=10.1002/gcc.20119
Raschke S., Balz V., Efferth T., Schulz W.A., Florl A.R.
Homozygous deletions of CDKN2A caused by alternative mechanisms in various human cancer cell lines.
Genes Chromosomes Cancer 42:58-67(2005)

PubMed=16331601; DOI=10.1002/ijc.21514
Muller A., Sonkoly E., Eulert C., Gerber P.A., Kubitza R., Schirlau K., Franken-Kunkel P., Poremba C., Snyderman C.H., Klotz L.-O., Ruzicka T., Bier H., Zlotnik A., Whiteside T.L., Homey B., Hoffmann T.K.
Chemokine receptors in head and neck cancer: association with metastatic spread and regulation during chemotherapy.
Int. J. Cancer 118:2147-2157(2006)

PubMed=18487078; DOI=10.1016/j.oraloncology.2008.02.006
Hoffmann T.K., Sonkoly E., Hauser U., van Lierop A., Whiteside T.L., Klussmann J.P., Hafner D., Schuler P.J., Friebe-Hoffmann U., Scheckenbach K., Erjala K., Grenman R., Schipper J., Bier H., Balz V.
Alterations in the p53 pathway and their association with radio- and chemosensitivity in head and neck squamous cell carcinoma.
Oral Oncol. 44:1100-1109(2008)

PubMed=26045983; PMCID=PMC4449432
Ziemann F., Arenz A., Preising S., Wittekindt C., Klussmann J.P., Engenhart-Cabillic R., Wittig A.
Increased sensitivity of HPV-positive head and neck cancer cell lines to X-irradiation +/- cisplatin due to decreased expression of E6 and E7 oncoproteins and enhanced apoptosis.
Am. J. Cancer Res. 5:1017-1031(2015)