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Cellosaurus L1210/6TG (CVCL_E2YF)

[Text version]
Cell line name L1210/6TG
Synonyms L1210/TG
Accession CVCL_E2YF
Resource Identification Initiative To cite this cell line use: L1210/6TG (RRID:CVCL_E2YF)
Comments Selected for resistance to: ChEBI; CHEBI:9555; Tioguanine (6-thioguanine; 6-TG).
Transformant: ChEBI; CHEBI:34342; 3-methylcholanthrene (3-MC; 20-methylcholanthrene; 20-MC; MCA).
Derived from site: In situ; Ascites; UBERON=UBERON_0007795.
Cell type: T-cell; CL=CL_0000084.
Disease Mouse leukemia (NCIt: C21604)
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: DBA/2.
Hierarchy Parent: CVCL_0382 (L1210)
Sex of cell Female
Age at sampling 8M
Category Cancer cell line
Publications

PubMed=13804596
Brockman R.W.
A mechanism of resistance to 6-mercaptopurine: metabolism of hypoxanthine and 6-mercaptopurine by sensitive and resistant neoplasms.
Cancer Res. 20:643-653(1960)

PubMed=6890814; DOI=10.1016/0006-2952(82)90096-x
Strobel-Stevens J.D., El Dareer S.M., Trader M.W., Hill D.L.
Some biochemical characteristics of L1210 cell lines resistant to 6-mercaptopurine and 6-thioguanine and with increased sensitivity to methotrexate.
Biochem. Pharmacol. 31:3133-3137(1982)

Entry history
Entry creation10-Sep-2024
Last entry update10-Sep-2024
Version number1