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Cellosaurus RAW 264.7 Lrrk2 KO + HALO-human LRRK2 LIR2 mutant + HA-human GABARAP (CVCL_E2X0)

[Text version]
Cell line name RAW 264.7 Lrrk2 KO + HALO-human LRRK2 LIR2 mutant + HA-human GABARAP
Synonyms RAW 264.7 LRRK2KO + HALO-LRRK2 (LIR2 mutant, human) + HA-Gabarap (human)
Accession CVCL_E2X0
Resource Identification Initiative To cite this cell line use: RAW 264.7 Lrrk2 KO + HALO-human LRRK2 LIR2 mutant + HA-human GABARAP (RRID:CVCL_E2X0)
Comments Knockout cell: Method=ZFN; MGI; MGI:1913975; Lrrk2.
Genetic integration: Method=Transfection; Gene=HGNC; HGNC:4067; GABARAP (Note=With a N-terminal HA tag).
Genetic integration: Method=Transfection; Gene=HGNC; HGNC:18618; LRRK2 (Note=With p.Trp875Ala and p.Ile878Ala).
Genetic integration: Method=Transfection; Gene=UniProtKB; P0A3G2; Rhodococcus rhodochrous dhaA (Note=Mutated = HaloTag).
Transformant: NCBI_TaxID; 11788; Abelson mouse leukemia virus (AbMuLV).
Derived from site: In situ; Ascites; UBERON=UBERON_0007795.
Cell type: Macrophage; CL=CL_0000235.
Disease Mouse leukemia (NCIt: C21604)
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: BALB/c.
Hierarchy Parent: CVCL_E2WY (RAW 264.7 Lrrk2 KO + HA-human GABARAP)
Sex of cell Male
Age at sampling Adult
Category Cancer cell line
Entry history
Entry creation10-Sep-2024
Last entry update19-Dec-2024
Version number2