ID   HCA2 [Human foreskin fibroblast]
AC   CVCL_E2UW
SY   HCA 2
DR   GEO; GSE198396
RX   PubMed=7753810;
RX   PubMed=9310070;
RX   PubMed=36323784;
CC   Omics: Transcriptomics; RNAseq.
CC   Derived from site: In situ; Foreskin, skin; UBERON=UBERON_0001471.
CC   Cell type: Fibroblast of foreskin; CL=CL_1001608.
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Male
AG   <1M
CA   Finite cell line
DT   Created: 10-09-24; Last updated: 10-04-25; Version: 2
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RX   PubMed=7753810; DOI=10.1073/pnas.92.10.4352; PMCID=PMC41942;
RA   Nakanishi, Makoto
RA   Adami, Guy R.
RA   Robetorye, Ryan S.
RA   Noda, Asao
RA   Venable, Susan F.
RA   Dimitrov, Diana
RA   Pereira-Smith, Olivia M.
RA   Smith, James R.
RT   "Exit from G0 and entry into the cell cycle of cells expressing
RT   p21Sdi1 antisense RNA.";
RL   Proc. Natl. Acad. Sci. U.S.A. 92:4352-4356(1995).
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RX   PubMed=36323784; DOI=10.1038/s41586-022-05388-4;
RA   Wang, Teh-Wei
RA   Johmura, Yoshikazu
RA   Suzuki, Narumi
RA   Omori, Satotaka
RA   Migita, Toshiro
RA   Yamaguchi, Kiyoshi
RA   Hatakeyama, Seira
RA   Yamazaki, Satoshi
RA   Shimizu, Eigo
RA   Imoto, Seiya
RA   Furukawa, Yoichi
RA   Yoshimura, Akihiko
RA   Nakanishi, Makoto
RT   "Blocking PD-L1-PD-1 improves senescence surveillance and ageing
RT   phenotypes.";
RL   Nature 611:358-364(2022).
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RX   PubMed=9310070; DOI=10.1093/gerona/52a.5.b229;
RA   Rubelj, Ivica
RA   Venable, Susan F.
RA   Lednicky, John
RA   Butel, Janet S.
RA   Bilyeu, Timothy
RA   Darlington, Gretchen J.
RA   Surmacz, Ewa
RA   Campisi, Judith
RA   Pereira-Smith, Olivia M.
RT   "Loss of T-antigen sequences allows SV40-transformed human cells in
RT   crisis to acquire a senescent-like phenotype.";
RL   J. Gerontol., A, Biol. Sci. Med. Sci. 52:B229-B234(1997).
//