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Cellosaurus HAP1 ATG9A-GFP-TEV-Flag clone 2A3 (CVCL_E2TR)

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Cell line name HAP1 ATG9A-GFP-TEV-Flag clone 2A3
Accession CVCL_E2TR
Resource Identification Initiative To cite this cell line use: HAP1 ATG9A-GFP-TEV-Flag clone 2A3 (RRID:CVCL_E2TR)
Comments Group: Haploid karyotype cell line.
Characteristics: Using CRISPR/Cas9 ATG9 been endogenously tagged at the C-terminus with an eGFP itself tagged by a TEV site followed by a FLAG tag (Direct_author_submission).
Genetic integration: Method=CRISPR/Cas9; Gene=FPbase; R9NL8; eGFP (Note=Enhanced GFP).
Miscellaneous: Cell line information from personal communication of Adriaenssens, Elias.
Derived from site: In situ; Bone marrow; UBERON=UBERON_0002371.
Sequence variations
  • Gene fusion; HGNC; HGNC:76; ABL1 + HGNC; HGNC:1014; BCR; Name(s)=BCR-ABL1, BCR-ABL; Note=BCR exon 13 fused to ABL1 exon 2 (b2a2 transcript) (from parent cell line).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Ser215Gly (c.643A>G); ClinVar=VCV000265337; Zygosity=Hemizygous (from parent cell line).
Disease Chronic myelogenous leukemia, BCR-ABL1 positive (NCIt: C3174)
Chronic myeloid leukemia (ORDO: Orphanet_521)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_Y019 (HAP1)
Sex of cell Male
Age at sampling 40Y
Category Cancer cell line
Entry history
Entry creation10-Sep-2024
Last entry update19-Dec-2024
Version number2