ID   HP-6b
AC   CVCL_E2TI
RX   PubMed=21208305;
CC   Population: Caucasian.
CC   Biotechnology: Used in assay systems for the detection of HPA-6b antibodies (PubMed=21208305).
CC   Sequence variation: Gene fusion; HGNC; 76; ABL1 + HGNC; 1014; BCR; Name(s)=BCR-ABL1, BCR-ABL; Note=BCR exon 14 fused to ABL1 exon 2 (b3a2 transcript) (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 11998; TP53; Simple; p.Gln136fs*13 (c.406_407insC); Zygosity=Homozygous (from parent cell line).
CC   Genetic integration: Method=Transfection/transduction; Gene=HGNC; 6138; ITGA2B.
CC   Genetic integration: Method=Transfection/transduction; Gene=HGNC; 6156; ITGB3 (Note=With p.Arg515Gln = HPA-6b/Ca(+)).
CC   Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P00552; Transposon Tn5 neo.
CC   Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P13249; S.alboniger pac (PuroR).
CC   Derived from site: In situ; Pleural effusion; UBERON=UBERON_0000175.
DI   NCIt; C9110; Blast phase chronic myelogenous leukemia, BCR-ABL1 positive
DI   ORDO; Orphanet_521; Chronic myeloid leukemia
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_0004 ! K-562
SX   Female
AG   53Y
CA   Cancer cell line
DT   Created: 10-09-24; Last updated: 10-09-24; Version: 1
//
RX   PubMed=21208305; DOI=10.1111/j.1365-3148.2010.01064.x;
RA   Hayashi T., Amakishi E., Matsuyama N., Yasui K., Furuta R.A., Hori Y.,
RA   Tanaka S., Fukumori Y., Hirayama F., Inoue M.;
RT   "Establishment of a cell line panel as an alternative source of
RT   platelet antigens for a screening assay of anti-human platelet
RT   antibodies.";
RL   Transfus. Med. 21:199-204(2011).
//