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Cellosaurus HP-18b (CVCL_E2TD)

[Text version]
Cell line name HP-18b
Accession CVCL_E2TD
Resource Identification Initiative To cite this cell line use: HP-18b (RRID:CVCL_E2TD)
Comments Population: Caucasian.
Biotechnology: Used in assay systems for the detection of HPA-18b antibodies (PubMed=23245717).
Genetic integration: Method=Transfection/transduction; Gene=HGNC; 6137; ITGA2 (Note=With p.Gln735His = HPA-18b/Cab(a)).
Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P13249; S.alboniger pac (PuroR).
Derived from site: In situ; Pleural effusion; UBERON=UBERON_0000175.
Sequence variations
  • Gene fusion; HGNC; 76; ABL1 + HGNC; 1014; BCR; Name(s)=BCR-ABL1, BCR-ABL; Note=BCR exon 14 fused to ABL1 exon 2 (b3a2 transcript) (from parent cell line).
  • Mutation; HGNC; 11998; TP53; Simple; p.Gln136fs*13 (c.406_407insC); Zygosity=Homozygous (from parent cell line).
Disease Blast phase chronic myelogenous leukemia, BCR-ABL1 positive (NCIt: C9110)
Chronic myeloid leukemia (ORDO: Orphanet_521)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0004 (K-562)
Sex of cell Female
Age at sampling 53Y
Category Cancer cell line
Publications

PubMed=23245717; DOI=10.2450/2012.0126-12; PMCID=PMC3934277
Hayashi T., Amakishi E., Matsuyama N., Yasui K., Furuta R.A., Hori Y., Tanaka S., Fukumori Y., Hirayama F.
Detection of anti-human platelet antibodies against integrin alpha2beta1 using cell lines.
Blood Transfus. 12 Suppl. 1:s273-s280(2014)

Entry history
Entry creation10-Sep-2024
Last entry update10-Sep-2024
Version number1