ID   MTC-22
AC   CVCL_E2T3
RX   PubMed=38573494;
CC   Population: Japanese.
CC   Doubling time: 18.3 +- 3.5 hours (PubMed=38573494).
CC   Sequence variation: Mutation; HGNC; HGNC:11110; ARID1A; Simple; p.Gln1346Ter (c.4036C>T); Zygosity=Homozygous (PubMed=38573494).
CC   Sequence variation: Mutation; HGNC; HGNC:8976; PIK3CB; Simple; p.Glu1051Lys (c.3151G>A); Zygosity=Homozygous (PubMed=38573494).
CC   Derived from site: In situ; Ovary; UBERON=UBERON_0000992.
ST   Source(s): PubMed=38573494
ST   Amelogenin: X
ST   CSF1PO: 10,11
ST   D13S317: 11
ST   D16S539: 9,11
ST   D18S51: 17
ST   D21S11: 29,33.2
ST   D3S1358: 16,17
ST   D5S818: 9,12
ST   D7S820: 11,12
ST   D8S1179: 12,13
ST   FGA: 21,22
ST   Penta D: 9,10
ST   Penta E: 14,18
ST   TH01: 7,8
ST   TPOX: 8
ST   vWA: 17,18
DI   NCIt; C40078; Ovarian clear cell adenocarcinoma
DI   ORDO; Orphanet_398971; Clear cell adenocarcinoma of the ovary
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Female
AG   46Y
CA   Cancer cell line
DT   Created: 10-09-24; Last updated: 19-12-24; Version: 2
//
RX   PubMed=38573494; DOI=10.1007/s13577-024-01058-x; PMCID=PMC11194194;
RA   Hoshino H., Inoue D., Shinagawa A., Yoshida H., Shigeto S., Matsuda K.,
RA   Akama T.O., Yoshida Y., Kobayashi M.;
RT   "Establishment of a human ovarian clear cell carcinoma cell line
RT   mutant in PIK3CB but not PIK3CA.";
RL   Hum. Cell 37:1184-1193(2024).
//