ID   OvBRCA1
AC   CVCL_E2T0
RX   PubMed=38615309;
CC   Sequence variation: Mutation; HGNC; HGNC:1100; BRCA1; Simple; p.Arg136Thrfs*5 (c.405_406del); Zygosity=Unspecified (PubMed=38615309).
CC   Genetic integration: Method=Transduction; Gene=HGNC; HGNC:11730; TERT.
CC   Genetic integration: Method=Transduction; Gene=MGI; MGI:88174; Bmi1.
CC   Genetic integration: Method=Transduction; Gene=UniProtKB; P03070; SV40 large T antigen.
CC   Genetic integration: Method=Transduction; Gene=FPbase; R9NL8; eGFP (Note=Enhanced GFP).
CC   Genetic integration: Method=Transduction; Gene=FPbase; KETFB; OFP (Note=Orange fluorescent protein from Cerianthus sp.).
CC   Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40).
CC   Omics: Transcriptome analysis by RNAseq.
CC   Derived from site: In situ; Ovary; UBERON=UBERON_0000992.
CC   Cell type: Epithelial cell of ovary; CL=CL_2000064.
DI   NCIt; C36100; BRCA1-associated hereditary breast and ovarian cancer syndrome
DI   ORDO; Orphanet_145; Hereditary breast and ovarian cancer syndrome
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Female
AG   57Y
CA   Transformed cell line
DT   Created: 10-09-24; Last updated: 19-12-24; Version: 2
//
RX   PubMed=38615309; DOI=10.1007/s13577-024-01064-z;
RA   Komatsu H., Okawa M., Kazuki Y., Kazuki K., Hichiwa G., Shimoya K.,
RA   Sato S., Taniguchi F., Oshimura M., Harada T.;
RT   "Characterization of immortalized ovarian epithelial cells with
RT   BRCA1/2 mutation.";
RL   Hum. Cell 37:986-996(2024).
//