Cellosaurus logo
expasy logo

Cellosaurus MCF-7GFP (CVCL_E2QM)

[Text version]
Cell line name MCF-7GFP
Synonyms MCF7GFP
Accession CVCL_E2QM
Resource Identification Initiative To cite this cell line use: MCF-7GFP (RRID:CVCL_E2QM)
Comments Population: Caucasian.
Doubling time: ~20-24 hours (DSMZ=ACC-983).
Genetic integration: Method=Transduction; Gene=FPbase; R9NL8; eGFP (Note=Enhanced GFP).
Derived from site: Metastatic; Pleural effusion; UBERON=UBERON_0000175.
Sequence variations
  • Gene deletion; HGNC; 1787; CDKN2A; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; 4172; GATA3; Simple; p.Asp336Glyfs*17 (c.1006dupG); Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; 8975; PIK3CA; Simple; p.Glu545Lys (c.1633G>A); ClinVar=VCV000013655; Zygosity=Heterozygous (from parent cell line).
Disease Invasive breast carcinoma of no special type (NCIt: C4194)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0031 (MCF-7)
Sex of cell Female
Age at sampling 69Y
Category Cancer cell line
STR profile Source(s): DSMZ=ACC-983

Markers:
AmelogeninX
CSF1PO10
D2S133821,23
D3S135816
D5S81812
D7S8208,9
D8S117910,14
D13S31711
D16S53911,12
D18S5114
D19S43313,14
D21S1130
FGA23,25
Penta D12
Penta E7,12
TH016
TPOX9,12
vWA14,15

Run an STR similarity search on this cell line
Publications

PubMed=29569804; DOI=10.1002/stem.2819
Melzer C., von der Ohe J., Hass R.
In vitro fusion of normal and neoplastic breast epithelial cells with human mesenchymal stroma/stem cells partially involves tumor necrosis factor receptor signaling.
Stem Cells 36:977-989(2018)

Cross-references
Cell line collections (Providers) DSMZ; ACC-983
Entry history
Entry creation10-Sep-2024
Last entry update10-Sep-2024
Version number1